Andrographolide Protects against LPS-Induced Acute Lung Injury by Inactivation of NF-κB

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Andrographolide Protects against LPS-Induced Acute Lung Injury by Inactivation of NF-κB

BACKGROUND Nuclear factor-κB (NF-κB) is a central transcriptional factor and a pleiotropic regulator of many genes involved in acute lung injury. Andrographolide is found in the plant of Andrographis paniculata and widely used in Traditional Chinese Medicine, exhibiting potently anti-inflammatory property by inhibiting NF-κB activity. The purpose of our investigation was designed to reveal the ...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2013

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0056407